128704-85-8 Usage
Uses
Used in Pharmaceutical Manufacturing:
(+)-a-Aminomethyl-o-chlorobenzyl alcohol is used as a reagent in the synthesis of pharmaceuticals for its ability to facilitate the creation of new drugs and medications, enhancing the range of available treatments.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
In the field of organic chemistry, (+)-a-Aminomethyl-o-chlorobenzyl alcohol is utilized as a chiral auxiliary, playing a crucial role in the production of enantiomerically pure compounds, which are essential for the development of effective and selective pharmaceuticals.
Used in Antiviral Applications:
(+)-a-Aminomethyl-o-chlorobenzyl alcohol has shown promising antiviral activity, making it a valuable compound in the development of treatments for viral infections.
Used in Antibacterial Applications:
Similarly, its antibacterial properties position (+)-a-Aminomethyl-o-chlorobenzyl alcohol as a potential agent in the fight against bacterial infections, contributing to the discovery of new antibiotics.
Check Digit Verification of cas no
The CAS Registry Mumber 128704-85-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,7,0 and 4 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 128704-85:
(8*1)+(7*2)+(6*8)+(5*7)+(4*0)+(3*4)+(2*8)+(1*5)=138
138 % 10 = 8
So 128704-85-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H10ClNO/c9-7-4-2-1-3-6(7)8(11)5-10/h1-4,8,11H,5,10H2
128704-85-8Relevant academic research and scientific papers
Aminoalcohols II: Preparation of Enantiomerically Pure Pharmacologically Active β-Aminoalcohols
Noe, C. R.,Knollmueller, M.,Gaertner, P.,Fleischhacker, W.,Katikarides, E.
, p. 481 - 494 (2007/10/02)
A synthesis of β-aminoalcohols is described starting from racemic or enantiomerically pure α-hydroxynitriles which were O-protected using enantiomerically pure acetal type protective groups.Reduction with lithium aluminium hydride yielded O-protected β-aminoalcohols.Whenever diastereomeric O-protected cyanohydrins could not be separated, the mixture was reduced and the resulting O-protected aminoalcohols were separated.Removal of the protective group using hydrogen chloride and methanol yielded enantiomerically pure β-aminoalcohols or their corresponding hydrochlorides. - Keywords: 1,2-Amino-alcohols, enantiomerically pure; Lithium aluminium hydride reduction
Efficient Asymmetric Reduction of Acyl Cyanides with B-3-Pinanyl-9-BBN (Alpine-Borane)
Midland, M. Mark,Lee, Penny E.
, p. 3237 - 3239 (2007/10/02)
Acyl cyanides are effectively reduced to optically active β-amino alcohols by using Alpine-Borane followed by sodium borohydride/cobaltous chloride