128706-26-3

Upstream product

• 133773-31-6 (E)-(4R,5R)-5-Benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-pent-2-enoic acid ethyl ester 
• 133604-44-1 (2S,3R)-3-Benzyloxy-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propionaldehyde 
• 100758-79-0 (2R,3R,4R)-3-Benzyloxy-1,2-O-isopropylidene-4-methyl-5-hexene-1,2-diol 
• 133604-43-0 (E)-(4R,5R)-5-Benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-pent-2-en-1-ol 

Downstream Products

• 133604-13-4 (2R,3R,4R,5R,6S,7S)-3-O-benzyl-7-O-((tert-butyldimethyl)silyl)-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 128706-27-4 (3R,4S,5S)-3-[(1R,2R)-2-Benzyloxy-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-methyl-ethyl]-5-methoxymethoxy-non-1-en-4-ol 
• 133604-22-5 (2R,3R,4R,5R/S,6R/S,7S,8R)-1,2:7,8-di-O-isopropylidene-4-methyl-5-vinyldecane-1,2,3,6,7,8-hexol 
• 133604-13-4 (2R,3R,4R,5R,6S,7R)-3-O-benzyl-7-O-((tert-butyldimethyl)silyl)-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 133604-16-7 (2R,3R,4R,5R,6S,7S)-3-O-benzyl-1,2:6,7-di-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 133604-16-7 (2R,3R,4R,5R,6S,7R)-3-O-benzyl-1,2:6,7-di-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 133604-14-5 (2R,3R,4R,5R,6S,7R)-3-O-benzyl-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 133604-14-5 (2R,3R,4R,5R,6S,7S)-3-O-benzyl-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 

Relevant academic research and scientific papers

Highly Felkin-Anh Selective Hiyama Additions of Chiral Allylic Bromides to Aldehydes. Application to the First Synthesis of Nephromopsinic Acid and Its Enantiomer

The chromium(II)-mediated addition ("Hiyama reaction") of the chiral allylic bromides 13, 15, 19, 22, 24, and 27 to achiral and chiral aldehydes proceeds with high Felkin-Anh selectivity with respect to the stereocenter at Cγ in the bromide (Table II). By