133604-13-4

Basic information

• Product Name: (2R,3R,4R,5R,6S,7S)-3-O-benzyl-7-O-((tert-butyldimethyl)silyl)-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol
• CAS NO: 133604-13-4
• Molecular Weight: 478.745
• Mol File: 133604-13-4.mol

Chemical Properties

• CAS DataBase Reference: (2R,3R,4R,5R,6S,7S)-3-O-benzyl-7-O-((tert-butyldimethyl)silyl)-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4R,5R,6S,7S)-3-O-benzyl-7-O-((tert-butyldimethyl)silyl)-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol(133604-13-4)
• EPA Substance Registry System: (2R,3R,4R,5R,6S,7S)-3-O-benzyl-7-O-((tert-butyldimethyl)silyl)-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol(133604-13-4)

Safety Data

• Hazardous Substances Data: 133604-13-4(Hazardous Substances Data)

Upstream product

• 133773-31-6 (E)-(4R,5R)-5-Benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-pent-2-enoic acid ethyl ester 
• 133604-43-0 (E)-(4R,5R)-5-Benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-pent-2-en-1-ol 
• 133604-44-1 (2S,3R)-3-Benzyloxy-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propionaldehyde 
• 100758-79-0 (2R,3R,4R)-3-Benzyloxy-1,2-O-isopropylidene-4-methyl-5-hexene-1,2-diol 
• 87727-28-4 (S)-2-tert-butyl-dimethyl-silanyloxy propanal 
• 128706-26-3 (R)-4-((E)-(1R,2R)-1-Benzyloxy-5-bromo-2-methyl-pent-3-enyl)-2,2-dimethyl-[1,3]dioxolane 
• 133604-42-9 (E)-(4S,5S)-5-Benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-pent-2-enoic acid ethyl ester 
• 133604-43-0 (E)-(4S,5S)-5-Benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-pent-2-en-1-ol 
• 120040-77-9 (2R,3S)-3-Benzyloxy-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propionaldehyde 
• 100572-69-8 (2R,3S,4S)-3-Bnzyloxy-1,2-O-isopropylidene-4-methyl-5-hexene-1,2-diol 
• 128632-65-5 (R)-4-((E)-(1S,2S)-1-Benzyloxy-5-bromo-2-methyl-pent-3-enyl)-2,2-dimethyl-[1,3]dioxolane 
• 74262-56-9 (2R)-2-(tert-butyldimethylsilyloxy)propanal 

Downstream Products

• 133604-16-7 (2R,3R,4R,5R,6S,7S)-3-O-benzyl-1,2:6,7-di-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 133604-14-5 (2R,3R,4R,5R,6S,7S)-3-O-benzyl-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 133604-16-7 (2R,3S,4S,5S,6R,7S)-3-O-benzyl-1,2:6,7-di-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 133604-19-0 (2R,3S,4S,5R,6R,7S)-3-O-benzyl-1,2:6,7-di-O-isopropylidene-4-methyl-5-O-((methylsulfonyl)methyl)octane-1,2,3,6,7-pentol 
• 133604-17-8 (2'R,2S,3S,4S,5R)-4-(benzyloxy)-2-((2',2-isopropylidenedioxy)propyl)-3-methyl-5,6-(isopropylidenedioxy)hexanal 
• 133604-18-9 (2R,3S,4S,5R,6R,7S)-3-O-benzyl-1,2:6,7-di-O-isopropylidene-5-(hydroxymethyl)-4-methyloctane-1,2,3,6,7-pentol 
• 133604-14-5 (2R,3S,4S,5S,6R,7S)-3-O-benzyl-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 133604-16-7 (2R,3R,4R,5R,6S,7R)-3-O-benzyl-1,2:6,7-di-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 
• 133604-14-5 (2R,3R,4R,5R,6S,7R)-3-O-benzyl-1,2-O-isopropylidene-4-methyl-5-vinyloctane-1,2,3,6,7-pentol 

Relevant articles and documents

Highly Felkin-Anh Selective Hiyama Additions of Chiral Allylic Bromides to Aldehydes. Application to the First Synthesis of Nephromopsinic Acid and Its Enantiomer

The chromium(II)-mediated addition ("Hiyama reaction") of the chiral allylic bromides 13, 15, 19, 22, 24, and 27 to achiral and chiral aldehydes proceeds with high Felkin-Anh selectivity with respect to the stereocenter at Cγ in the bromide (Table II). By