128708-52-1

Basic information

• Product Name: Benzoic acid (1R,2R)-2-benzoylamino-1-(dimethoxy-phosphoryl)-propyl ester
• CAS NO: 128708-52-1
• Molecular Weight: 391.361
• Mol File: 128708-52-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid (1R,2R)-2-benzoylamino-1-(dimethoxy-phosphoryl)-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid (1R,2R)-2-benzoylamino-1-(dimethoxy-phosphoryl)-propyl ester(128708-52-1)
• EPA Substance Registry System: Benzoic acid (1R,2R)-2-benzoylamino-1-(dimethoxy-phosphoryl)-propyl ester(128708-52-1)

Safety Data

• Hazardous Substances Data: 128708-52-1(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 23155-02-4 fosfomycin 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Biosynthesis of Natural Products with a P-C Bond, V. - The Oxirane Oxygen Atom of Fosfomycin Is not Derived from Atmospheric Oxygen

Fosfomycin (1) in the culture broth of Streptomyces fradiae was transformed into (amino-hydroxypropyl)phosphonic acids 12 and 13.The main product 12 was isolated by ion-exchange chromatography.Streptomyces fradiae grown in an 18O2-enriched atmosphere produced unlabelled fosfomycin.For comparison 18O-labelled diastereomeric (2-amino-1-hydroxypropyl)phosphonic acids 16 and 17 showing an α shift of 0.025 ppm in the 13C-NMR spectrum were prepared starting from Boc-L-alaninal. (Z)-1-Propenylphosphonic acid was not incorporated into 1.D-Glucose afforded 12 with 16percent deuterium at C1.