128746-80-5 Usage
Description
2-BROMO-1-[4-(2-THIENYL)PHENYL]-1-ETHANONE, also known as 4-bromo-2-thiophen-2-ylacetophenone, is a chemical compound characterized by its molecular formula C14H11BrOS. It is a yellow crystalline solid with a molecular weight of 301.2 g/mol. 2-BROMO-1-[4-(2-THIENYL)PHENYL]-1-ETHANONE is distinguished by the presence of a bromine atom and a thienyl group in its structure, which endows it with unique chemical and pharmaceutical properties. It is a valuable building block in organic synthesis due to its versatile reactivity and potential applications in the development of new compounds.
Uses
Used in Pharmaceutical Synthesis:
2-BROMO-1-[4-(2-THIENYL)PHENYL]-1-ETHANONE is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications, including the treatment of various diseases and conditions.
Used in Agrochemical Production:
In the agrochemical industry, 2-BROMO-1-[4-(2-THIENYL)PHENYL]-1-ETHANONE serves as an important intermediate for the production of various agrochemicals. Its chemical properties make it suitable for the synthesis of compounds with pesticidal, herbicidal, or other agricultural applications, contributing to the development of more effective and environmentally friendly products.
Used in Organic Compounds Production:
2-BROMO-1-[4-(2-THIENYL)PHENYL]-1-ETHANONE is also utilized in the production of various organic compounds. Its reactivity and structural features make it a valuable precursor for the synthesis of a wide range of organic molecules, including those with potential applications in materials science, chemical research, and other fields.
Used as a Chemical Intermediate:
Due to its unique structure and reactivity, 2-BROMO-1-[4-(2-THIENYL)PHENYL]-1-ETHANONE is commonly used as an intermediate in the synthesis of other chemicals and pharmaceuticals. Its presence in the chemical library allows for the exploration of new synthetic pathways and the development of innovative compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 128746-80-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,7,4 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 128746-80:
(8*1)+(7*2)+(6*8)+(5*7)+(4*4)+(3*6)+(2*8)+(1*0)=155
155 % 10 = 5
So 128746-80-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H9BrOS/c13-8-11(14)9-3-5-10(6-4-9)12-2-1-7-15-12/h1-7H,8H2
128746-80-5Relevant articles and documents
Lipid-lowering (hetero)aromatic tetrahydro-1,4-oxazine derivatives with antioxidant and squalene synthase inhibitory activity
Kourounakis, Angeliki P.,Charitos, Christos,Rekka, Eleni A.,Kourounakis, Panos N.
supporting information; experimental part, p. 5861 - 5865 (2009/09/25)
A number of newly synthesized 2-[4-(hetero)aromatic]phenyl-2-hydroxy- tetrahydro-1,4-oxazine derivatives were found to inhibit lipid peroxidation (IC50 of the most potent was 20 μM) as well as rat squalene synthase (IC50 for most between 1-10 μM). Antidyslipidemic action was demonstrated in vivo: the most active compound decreased triglycerides, total cholesterol, and LDL-cholesterol of hyperlipidemic rats by 64, 67, and 82%, respectively, at 56 μmol/kg (ip). Most of the novel compounds are more active than the structurally related and reference biphenyl-morpholine, pointing to useful structural approaches for the design of antiatherosclerotic agents.
