128752-86-3Relevant academic research and scientific papers
Direct Copper-Catalyzed C-H Monofluoroalkylation of Benzoxazoles with 1-Fluoro-1-haloalkanes
Li, Wei,Varenikov, Andrii,Gandelman, Mark
supporting information, p. 3138 - 3141 (2020/03/13)
The first example of direct C–H bond monofluoroalkylation with 1-fluoro-1-haloalkanes with no adjacent functional groups and with β-hydrogens has been developed. This transformation offers a straightforward route for the synthesis of a series of monofluoroalkylated benzoxazoles.
Ring opening of cyclopropanemonocarboxylates and 1,1- cyclopropanedicarboxylates using samarium(II) diiodide (SmI2)-HMPA-THF system
Yamashita,Okuyama,Ohhara,Kawasaki,Sakai,Nakata,Kawabe,Kusumoto,Ohta
, p. 2075 - 2081 (2007/10/03)
The cyclopropane ring in 2-substituted 1,1-cyclopropanedicarboxylates was regioselectively opened by using samarium(II) diiodide (Sml2) in a hexamethylphosphoric triamide (HMPA)-tetrahydrofuran (THF) (1:10) system under mild and neutral conditions to give (2-substituted ethyl)malonates in moderate to good yields. The cyclopropane ring in 2-substituted cyclopropanecarboxylates or 2-substituted 3- (trimethylsilyl)cyclopropanecarboxylates was similarly cleaved regioselectively by using Sml2 in a HMPA-THF (1:1) system to give 4- arylbutyrates or 4-aryl-3-(trimethylsilyl)butyrates in 16-89% yields. The reaction mechanism of these ring-opening reactions is discussed.
Relative Rates for the Addition Reactions of the Malonyl Radical to Substituted Styrenes Induced by Cerium(IV) Ammonium Nitrate and Tributyltin Hydride. A Comparison
Baciocchi, Enrico,Giese, Bernd,Farshchi, Hassan,Ruzziconi, Renzo
, p. 5688 - 5691 (2007/10/02)
The relative rates for the addition reactions of the malonyl radical to substituted styrenes induced by cerium(IV) ammonium nitrate (CAN) and tributyltin hydride have been determined.The two processes exhibit practically identical ρ+ values (-1.05 and -1.06), thus suggesting that the coordination between the metal and the radical does not play a significant role in the CAN-promoted oxidative additions.
