128757-40-4Relevant academic research and scientific papers
POTENTIAL CNS ACTIVE 1-ARYL-2-AMINO-1-ETHANOL DERIVATIVES
Zara-Kaczian, Erzsebet,Deak, Gyula,Gyoergy, Lajos
, p. 441 - 454 (2007/10/02)
New N-(picolyl)-2-(methylamino)-1-aryl-1-ethanols (I) and their O-acyl derivatives (II) were synthesized.Their dopaminomimetic and antidepressant biological activities were examined and compared with the activities of N-(2-aminobenzyl)-2-(methylamino)-1-aryl-1-ethanols (III).It was established that in the reaction of N- methylamine (2) and styryl oxide, the two directions of the splitting of the epoxide ring give rise to two different products that were isolated and identified in the form of their O-acetyl derivatives (13 and 15, respectively).
