128764-53-4

Upstream product

• 445-29-4 o-fluoro-benzoic acid 

Downstream Products

• 445-29-4 o-fluoro-benzoic acid 
• 66464-26-4 2-(2,6-difluorophenyl)-4,5-dihydro-4,4-dimethyl-1,3-oxazole 
• 66464-20-8 2-(2-fluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 
• 64691-33-4 2-[2-(diphenylphosphino)phenyl]-4,4-dimethyl-4,5-dihydro-1,3-oxazole 
• 179116-95-1 N-(2-chloro-1,1-dimethyl-ethyl)-2-fluoro-benzamide 

Relevant academic research and scientific papers

Palladium-catalyzed electrophilic C–H fluorination of arenes using oxazoline as a removable directing group

Dimethyloxazoline was rationally designed to act as a removable ortho-directing group (DG) for the palladium-catalyzed C–H electrophilic fluorination of arenes. Using NFSI as the fluorinating agent, and Pd(II), Ag(I) catalytic system, electrophilic C(sp2–H) ortho-fluorination took place on a variety of aryl substrates to afford the corresponding mono- and di-fluorinated products.

Amide derivative

A compound of the formula: wherein Ar is optionally substituted phenyl, etc.; n is 0, 1 or 2; R1is hydogen atom, optionally substituted alkyl, etc.; R2and R3are independently optionally substituted alkyl, etc.; R4and R5are independently hydrogen atom or optionally substituted alkyl; R6is hydrogen atom, hydroxy or alkyl; or a pharmaceutically acceptable salt thereof is useful as a medicament for treating retinal degenerative disorders and the like.