128807-55-6

Upstream product

• 275371-05-6 2-bromo-2-(4-chloro-phenyl)-N-methoxy-acetamide 
• 121090-07-1 N-[3,4-Bis-(4-chloro-phenyl)-2,5-dioxo-2,5-dihydro-pyrrol-1-yl]-benzamide 
• 121090-04-8 [3,4-Bis-(4-chloro-phenyl)-2,5-dioxo-2,5-dihydro-pyrrol-1-yl]-carbamic acid methyl ester 
• 504-29-0 2-aminopyridine 
• 110520-29-1 Benzoic acid N'-[2-bromo-2-(4-chloro-phenyl)-acetyl]-hydrazide 
• 110520-34-8 N'-[2-Bromo-2-(4-chloro-phenyl)-acetyl]-hydrazinecarboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis in a stage of N-methoxyindolinones, N-methoxymaleimides and maleic anhydrides starting from α-halogen hydroxamic acids

α-Halo hydroxamic acids were used in the synthesis of N-methoxyindolinones, symmetric and dissymmetric N-methoxymaleimides in good yields. The hydrolysis of N-methoxymaleimides constitues a new and good route to maleic anhydrides.

SYNTHESE DE N-AMINO MALEIMIDES ET D'ANHYDRIDES MALEIQUES DISUBSTITUES A PARTIR D'α-HALOGENO HYDRAZIDES. ETUDE DU MECANISME DE LA REACTION.

α-Halohydrazides react with 2-aminopyridine to give symmetrically substituted N-aminomaleimides.We have shown that this reaction proceeds through the formation of 4-hydroxyimidazopyridines.This result opens a new route to dissymetrically substituted N-aminomaleimides.The hydrolysis of N-aminomaleimides is a grood route to substituted maleic anhydrides.

A New Synthetic Route to N-Amino Maleimides

N-Amino maleimides have been obtained in good yield through the reaction of α-halohydrazides with N-aminopyridine.