128864-40-4Relevant academic research and scientific papers
Regioselective synthesis of [1,2,3]-triazoles catalyzed by Cu(I) generated in situ from Cu(0) nanosize activated powder and amine hydrochloride salts
Orgueira, Hernán A.,Fokas, Demosthenes,Isome, Yuko,Chan, Philip C.-M.,Baldino, Carmen M.
, p. 2911 - 2914 (2005)
A straightforward and efficient method for the regioselective synthesis of functionalized 1,4-disubstituted [1,2,3]-triazoles, from terminal alkynes and azides, has been established utilizing Cu(0) as the source of the catalytic species. The presumed cata
Superoxide dismutase-like activity of 1,2,3-triazole derivatives.
Biagi,Livi,Ramacciotti,Scartoni,Bazzichi,Mazzoni,Lucacchini
, p. 49 - 57 (2007/10/02)
This paper reports the synthesis of some sulfurated 1,2,3-triazole derivatives and the biological evaluation, for the superoxide dismutase-like activity, of these new compounds together with several 1,2,3-triazoles previously described by us. All the compounds possess a SOD-like activity and some of them showed an activity equivalent to or higher than those of penicillamine or thiopronin, which are well known therapeutic drugs in the treatment of rheumatoid arthritis.
