1289139-29-2

Basic information

• Product Name: 7H-Pyrazolo[4,3-d]pyriMidin-7-one, 1,6-dihydro-3-(1-Methylethyl)-5-(Methylthio)-
• Synonyms: 7H-Pyrazolo[4,3-d]pyriMidin-7-one, 1,6-dihydro-3-(1-Methylethyl)-5-(Methylthio)-
• CAS NO: 1289139-29-2
• Molecular Formula: C9H12N4OS
• Molecular Weight: 224.28278
• Mol File: 1289139-29-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 443.4±47.0 °C(Predicted)
• Appearance: /
• Density: 1.51±0.1 g/cm3(Predicted)
• PKA: 11.87±0.20(Predicted)
• CAS DataBase Reference: 7H-Pyrazolo[4,3-d]pyriMidin-7-one, 1,6-dihydro-3-(1-Methylethyl)-5-(Methylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 7H-Pyrazolo[4,3-d]pyriMidin-7-one, 1,6-dihydro-3-(1-Methylethyl)-5-(Methylthio)-(1289139-29-2)
• EPA Substance Registry System: 7H-Pyrazolo[4,3-d]pyriMidin-7-one, 1,6-dihydro-3-(1-Methylethyl)-5-(Methylthio)-(1289139-29-2)

Safety Data

• Hazardous Substances Data: 1289139-29-2(Hazardous Substances Data)

Upstream product

• 1289139-26-9 3-isopropyl-5-sulfanyl-1⁽²⁾H-pyrazolo[4,3-d]pyrimidine-7-ol 
• 77-78-1 dimethyl sulfate 
• 521300-03-8 4-amino-5-isopropyl-1⁽²⁾H-pyrazole-3-carboxamide 

Downstream Products

• 1289139-34-9 7-benzylamino-3-isopropyl-5-methylsulfonyl-1H-pyrazolo[4,3-d]pyrimidine 

Relevant articles and documents

Pyrazolo[4,3- d ]pyrimidine bioisostere of roscovitine: Evaluation of a novel selective inhibitor of cyclin-dependent kinases with antiproliferative activity

Inhibition of cyclin-dependent kinases (CDKs) with small molecules has been suggested as a strategy for treatment of cancer, based on deregulation of CDKs commonly found in many types of human tumors. Here, a new potent CDK2 inhibitor with pyrazolo[4,3-d]