128916-30-3

Basic information

• Product Name: (4-methylpyridyl)(4-methylphenyl)sulfide
• Synonyms: (4-methylpyridyl)(4-methylphenyl)sulfide
• CAS NO: 128916-30-3
• Molecular Weight: 215.319
• Mol File: 128916-30-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (4-methylpyridyl)(4-methylphenyl)sulfide(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methylpyridyl)(4-methylphenyl)sulfide(128916-30-3)
• EPA Substance Registry System: (4-methylpyridyl)(4-methylphenyl)sulfide(128916-30-3)

Safety Data

• Hazardous Substances Data: 128916-30-3(Hazardous Substances Data)

Upstream product

• 108-89-4 picoline 
• 106-45-6 para-thiocresol 
• 1822-51-1 4-picolylchloride hydrochloride 
• 10445-91-7 4-(Chloromethyl)pyridine 

Downstream Products

• 106-45-6 para-thiocresol 
• 128916-38-1 4-[1-(Toluene-4-sulfinyl)-ethyl]-pyridine 
• 128916-32-5 4-pyridylmethyl p-tolyl sulfoxide 

Relevant articles and documents

Nickel-catalyzed oxidative dehydrogenative coupling of alkane with thiol for C(sp3)-S bond formation

A nickel-catalyzed oxidative dehydrogenative coupling reaction of alkane with thiol for the construction of C(sp3)-S bond has been established, affording more than 50 alkyl thioethers. Notably, pharmaceutical and agrochemicals, such as Provigil, Chlorbenside and Pyridaben, were readily synthesized by this approach. The sterically hindered ligand BC and disulfide which was formed in situ oxidation of thiol, efficiently avoiding nickel-catalyst poisoning. A set of mechanistic experiments disclose both Ni-catalyzed and Ni-free HAA processes.

A mild method for the cleavage of the 4-picolyloxy group with magnesium under neutral conditions

A mild and efficient method for the selective hydrolysis of 4-picolyl esters with magnesium in methanol or water in the presence of other esters and sensitive protecting groups is described. 4-Picolyl aryl ethers and thioethers are also smoothly deprotected to give the corresponding phenols and thiophenols. Georg Thieme Verlag Stuttgart. New York.