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Clarithromycin EP Impurity F, also known as 12-O-Methyl Clarithromycin, is a methylated impurity derived from the semi-synthetic macrolide antibiotic Clarithromycin (C559750). It has been identified for its inhibitory effect on the uptake of Clarithromycin into lung cells, which is significant in understanding the behavior and efficacy of the parent antibiotic.

128940-83-0

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128940-83-0 Usage

Uses

Used in Pharmaceutical Quality Control:
Clarithromycin EP Impurity F is used as a reference impurity for quality control purposes in the pharmaceutical industry. It helps ensure the purity and potency of Clarithromycin, a widely used antibiotic, by providing a benchmark for impurity testing and assessment.
Used in Research and Development:
In the field of pharmaceutical research and development, Clarithromycin EP Impurity F serves as a crucial tool for studying the interactions between the parent antibiotic and lung cells. This research can lead to a better understanding of the drug's absorption, distribution, and overall effectiveness in treating respiratory infections.
Used in Regulatory Compliance:
Clarithromycin EP Impurity F is also utilized in regulatory compliance processes to ensure that pharmaceutical manufacturers adhere to established standards for drug quality and safety. By monitoring for the presence of this impurity, regulatory bodies can help protect consumers from potentially harmful or ineffective medications.

Check Digit Verification of cas no

The CAS Registry Mumber 128940-83-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,9,4 and 0 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 128940-83:
(8*1)+(7*2)+(6*8)+(5*9)+(4*4)+(3*0)+(2*8)+(1*3)=150
150 % 10 = 0
So 128940-83-0 is a valid CAS Registry Number.

128940-83-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 12-O-Methyl Clarithromycin

1.2 Other means of identification

Product number -
Other names (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12-hydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7,13-dimethoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dion

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:128940-83-0 SDS

128940-83-0Upstream product

128940-83-0Downstream Products

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