1289557-72-7

Upstream product

• 108182-63-4 (E)-3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-α-D-xylo-hept-5-eno-1,4-furanose 
• 108788-49-4 ethyl (E)-[3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-α-D-gluco]-heptofuran-5-en-uronate 
• 1289557-54-5 (E)-5,6-dideoxy-1,2-O-isopropylidene-3-O-triizopropylsilyl-α-D-xylo-hept-5-enfuranose 
• 1289557-70-5 C₁₈H₂₃NO₈ 
• 74-88-4 methyl iodide 
• 1289557-68-1 5,6,7-trideoxy-1,2-O-isopropylidene-5-(methoxycarbonylamino)-α-D-gluco-hept-6-enfuranose 
• 1289557-66-9 3-O-benzyl-5,6,7-trideoxy-1,2-O-isopropylidene-5-(methoxycarbonylamino)-α-D-gluco-hept-6-enfuranose 
• 1289557-49-8 C₂₁H₃₈O₆Si 
• 1289557-64-7 5,6,7-trideoxy-1,2-O-isopropylidene-3-O-triisopropylsilyl-5-(methoxycarbonylamino)-α-D-gluco-hept-6-enfuranose 
• 1289557-80-7 C₂₁H₃₉NO₅SSi 
• 1289557-62-5 3-O-benzyl-5,6,7-trideoxy-1,2-O-isopropylidene-5-(methoxythiocarbonylamino)-α-D-gluco-hept-6-enfuranose 
• 1289557-60-3 5,6,7-trideoxy-1,2-O-isopropylidene-3-O-triisopropylsilyl-5-isothiocyanato-α-D-gluco-hept-6-enfuranose 
• 1289557-58-9 3-O-benzyl-5,6,7-trideoxy-1,2-O-isopropylidene-5-isothiocyanato-α-D-gluco-hept-6-enfuranose 
• 1289557-57-8 (E)-5,6,7-trideoxy-1,2-O-isopropylidene-3-O-triisopropylsilyl-7-thiocyanato-α-D-xylo-hept-5-enfuranose 

Downstream Products

• 1289557-76-1 methyl 1,2-di-O-acetyl-3-O-benzyl-5-deoxy-5-(methoxycarbonylamino)-α-D-gluco-hexofuranuronate 
• 1289557-78-3 methyl 1,2-di-O-acetyl-3-O-benzyl-5-deoxy-5-(methoxycarbonylamino)-β-D-gluco-hexofuranuronate 

Relevant academic research and scientific papers

A short stereoselective synthesis of the protected uracil 3′-epi-polyoxin C

A short synthetic approach to the protected uracil 3′-epi-polyoxin C 20 has been developed. The stereoselective [3,3]-sigmatropic rearrangement of the corresponding 7-thiocyanato-α-d-xylo-hept-5-enfuranose 6 was employed as the key step to construct the C-5 stereocentre in 5-isothiocyanato-α-d- gluco-hept-6-enfuranose 8 and the formal synthesis of uracil 3′-epi-polyoxin C has been accomplished for the first time. This synthesis provides a facile method for multigram scale preparation and thus is useful for the research into the polyoxins' structure-activity relationship and to search for more potent and effective anticandidal agents.