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Upstream product

• 100-52-7 benzaldehyde 
• 70499-16-0 4a′-methyl-4′,4a′,7′,8′-tetrahydro-3′H-spiro[[1,3]dithiolane-2,2′-naphthalen]-5′(6′H)-one 

Relevant academic research and scientific papers

Structural requirements of (E)-6-benzylidene-4a-methyl-4,4a,5,6,7,8- hexahydronaphthalen-2(3H)-one derivatives as novel melanogenesis inhibitors

Chalcone type compound 1a ((E)-6′-benzylidene-4a′-methyl- 4′,4a′,7′,8′-tetrahydro-3′H-spiro[[1,3] dithiolane-2,2′-naphthalen]-5′(6′H)-one) was discovered as an potent inhibitor in melanogenesis. To define its structure-activity relationship, a series of a