128965-40-2Relevant academic research and scientific papers
THE PICTET-SPENGLER REACTION OF Nb-HYDROXYTRYPTAMINES AND CYSTEINALS. I. ISOLATION OF TETRACYCLIC INTERMEDIATES AND FORMATION OF OPTICALLY ACTIVE Nb-HYDROXY-TETRAHYDRO-β-CARBOLINES
Liu, Jinjun,Nakagawa, Masako,Hino, Tohru
, p. 7729 - 7742 (2007/10/02)
The Pictet-Spengler(P-S) reaction of Nb-hydroxytryptamines 5 and cysteinals 6 in the presence of trifluoroacetic acid(TFA) at room temperature gave the tetracyclic compounds 7α as well as the corresponding Nb-hydroxy-β-carbolines 8.The optically active nitrones 9, isolated from the similar reaction of 5 and optically active 6, gave optically active 7α and 8.
