128967-40-8Relevant academic research and scientific papers
Magnetic Fe3O4 nanoparticle-supported phosphotungstic acid as a recyclable catalyst for the kabachnik-fields reaction of isatins, imines, and aldehydes under solvent-free conditions
Nazish, Mohd,Saravanan,Khan, Noor-Ul H.,Kumari, Prathibha,Kureshy, Rukhsana I.,Abdi, Sayed H. R.,Bajaj, Hari C.
, p. 1753 - 1760 (2015/02/02)
Magnetic-nanoparticle-supported phosphotungstic acid has been used to efficiently catalyze the hydrophosphonylation reaction of isatins, imines, and aldehydes using dimethyl and diethyl phosphite as a nucleophile to give the corresponding α-hydroxy and α-amino phosphonates in excellent yields for a wide range of substrates. The reaction conditions were simple, green, and efficient. The catalyst was recycled up to five times with retention of its activity. Based on the NMR spectroscopy studies, a probable catalytic cycle was proposed.
The Behaviour of 3-Aryliminoxindoles toward Alkyl Phosphites
Abdou, Wafaa M.,Abd El-Rahman, Naglaa M.,Mahran, Mohamed R. H.
, p. 906 - 912 (2007/10/02)
3-Aryliminoxindoles (6a-c) react with trialkyl phosphites (TAP, 2a-c) only in presence of a protonating agent (H2O or CH3COOH) to give the respective dialkyl 3-(arylamino-2-oxo-1H-indol-3-yl)-phosphonates (9a-i).Compounds 9 are equally obtained by reacting 6a-c with the appropriate dialkyl phosphite (DAP, 4a-c) in absence of solvent.The role displayed by the arylimine-moiety on the reaction courses is discussed.A mechanism that accounts for formation of 9 from the reaction of anils 6 with TAP, is presented.Structural assignment are based upon analytical, chemical and spectroscopic (i.r., 1H-n.m.r., 31P-n.m.r. and m.s.) results.
