128970-38-7

Basic information

• Product Name: tert-butyloxycarbonyl-anthranilic acid-prolinmethylester
• CAS NO: 128970-38-7
• Molecular Weight: 348.399
• Mol File: 128970-38-7.mol

Chemical Properties

• CAS DataBase Reference: tert-butyloxycarbonyl-anthranilic acid-prolinmethylester(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyloxycarbonyl-anthranilic acid-prolinmethylester(128970-38-7)
• EPA Substance Registry System: tert-butyloxycarbonyl-anthranilic acid-prolinmethylester(128970-38-7)

Safety Data

• Hazardous Substances Data: 128970-38-7(Hazardous Substances Data)

Upstream product

• 109-02-4 4-methyl-morpholine 
• 68790-38-5 2-(tert-butyloxycarbonylamino)benzoic acid 
• 43041-12-9 methyl pyrrolidine-2-carboxylate 

Relevant articles and documents

Conformation of Anthranilic Acid Peptides, 3(1): Conformation of small Anthranilic-Acid-Prolie-peptides inm Cristal, in Solution and a Semie-Empirical (AM1) Description of the Proline-Ramachandran-Maps

Starting from tert-Butyloxycarbonyl(BOC)-Anthranilic-Acid(Abz) (1), BOC-Abz-Proline-Methyl-Ester (2) is synthesized.The crystal structure of both compounds are discussed.The conformational features of the crystal structures of 2 are compared with the conformation in solution.The whole conformational area (Φ and Ψ) of the amino acid part of 2 was investigated with the semi-empirical quantummechanical method AM1, in order to check the general availability of the influence of ester functions to depsipeptide conformations.Cyclo-anthranoyl-prolinyl (3), which had already been described in the literature, forms crystals with a high density.Two independent molecules are found in the crystal structure; these molecules have very similar conformations.