128970-49-0Relevant academic research and scientific papers
Palladium(0)- and nickel(0) catalyzed "metallo-ene-type" cyclizations: Stereodirecting resident chirality
Oppolzer, Wolfgang,Keller, Thomas H.,Kuo, David L.,Pachinger, Werner
, p. 1265 - 1268 (1990)
Trans-cyclization products were selectively formed from C-6-substituted acetoxy-octadienes only via Ni(0) catalysis (1 → 2) and from C-4-substituted analogs under Pd(0)- and Ni(0) catalysis (7, 8 → 9). C-5-Substituted precursors gave mixtures of diastereoisomers. Nickel(0) catalyzed allylation/methoxycarbonylation of iodo diene 11 afforded 2-oxa-bicyclo[3.3.0]octanone 12 with highly diastereoselective generation of three stereogenic centers.
