128997-54-6Relevant academic research and scientific papers
Preparation and antiarthritic activity of new 1,5-diaryl-3-alkylthio-1H-1,2,4-triazoles and corresponding sulfoxides and sulfones
Szilagyi, Geza,Somorai, Tamas,Bozo, Eva,Lango, Jozsef,Nagy, Gabor,et al.
, p. 95 - 101 (2007/10/02)
A series of 1,5-diaryl-3-alkylthio-1H-1,2,4-triazoles and corresponding sulfoxides and sulfones was synthesized and evaluated as antiinflammatory agents in the rat adjuvant induced arthritis assay.Several analogues were found to be more potent than phenyl
SYNTHETIC STUDIES ON NOGALAMYCIN CONGENERS ; SYNTHESES AND ANTITUMOR ACTIVITY OF VARIOUS NOGALAMYCIN CONGENERS
Matsuda, Fuyuhiko,Kawasaki, Motoji,Ohsaki, Masako,Yamada, Kaoru,Terashima, Shiro
, p. 5745 - 5760 (2007/10/02)
Various structural types of nogalamycin congeners and their partial structures, which had been previously synthesized in the course of our synthetic studies on the total syntheses or were originally produced by employing the explored synthetic scheme, were subjected to in vitro cytotoxicity and in vivo antitumor activity assay against P388 murine leukemia.These studies obviously disclosed novel aspects of the structure-activity relationships of nogalamycin congeners.
