1290042-56-6Relevant articles and documents
Specific biotinylation of IMP dehydrogenase
Hoefler, B. Christopher,Gollapalli, Deviprasad R.,Hedstrom, Lizbeth
, p. 1363 - 1365 (2011)
IMP dehydrogenase (IMPDH) catalyzes a critical step in guanine nucleotide biosynthesis. IMPDH also has biological roles that are distinct from its enzymatic function. We report a biotin-linked reagent that selectively labels IMPDH and is released by dithiothreitol. This reagent will be invaluable in elucidating the moonlighting functions of IMPDH.