1290176-58-7Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of novel benzoylazole-based PPAR α/γ activators
Ushiroda, Kantaro,Maruta, Katsunori,Takazawa, Takeshi,Nagano, Tomokazu,Taiji, Mutsuo,Kohno, Tetsuya,Sato, Yasuhiro,Horai, Shinji,Yanagi, Kazunori,Nagata, Ryu
, p. 1978 - 1982 (2011/04/24)
In our search for new PPARα/γ agonists, we designed and synthesized a series of benzoylazole-based carboxylic acids. Compound 9 showed potent PPARγ partial agonistic activity with modest PPARα agonistic activity. The sodium salt of 9 (9Na) demonstrated po
