129053-70-9

Usage

Uses

Used in Organic Synthesis:
2-Bromo-5-phenyl-1,3-oxazole serves as a valuable building block in organic synthesis, contributing to the creation of a wide range of chemical compounds. Its unique structure allows for various chemical reactions, facilitating the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-bromo-5-phenyl-1,3-oxazole is utilized for the synthesis of pharmaceuticals and biologically active molecules. Its presence in these molecules can potentially enhance their therapeutic effects, making it a promising candidate for drug development.
Used in Pharmaceutical Development:
2-Bromo-5-phenyl-1,3-oxazole is employed as a key component in the development of new pharmaceuticals. Its incorporation into drug molecules can improve their efficacy, selectivity, and pharmacokinetic properties, leading to the discovery of novel therapeutic agents.
Used in Anti-Inflammatory Applications:
2-Bromo-5-phenyl-1,3-oxazole has been studied for its potential anti-inflammatory properties. It may be used as an anti-inflammatory agent to alleviate inflammation and associated symptoms, offering a new approach to treating inflammatory conditions.
Used in Antimicrobial Applications:
2-bromo-5-phenyl-1,3-oxazole has also been investigated for its antimicrobial properties, making it a potential candidate for use in antimicrobial agents. Its ability to combat microbial infections could contribute to the development of new antibiotics and antifungal drugs, addressing the growing issue of antibiotic resistance.
Used in Research and Development:
2-Bromo-5-phenyl-1,3-oxazole is a versatile compound with applications in various research and development fields. Its unique structure and properties make it an attractive candidate for exploring new chemical reactions, synthesis pathways, and potential applications in material science, agrochemistry, and other related disciplines.

InChI:InChI=1/C9H6BrNO/c10-9-11-6-8(12-9)7-4-2-1-3-5-7/h1-6H

Upstream product

• 1006-68-4 5-phenyloxazole 
• 98-88-4 benzoyl chloride 
• 129053-62-9 1-benzoyl-3-bromo-1,2,4-triazole 

Relevant academic research and scientific papers

A simple base-mediated halogenation of acidic sp2 C-H bonds under noncryogenic conditions

(Chemical Equation Presented) A new method has been developed for in situ halogenation of acidic sp2 carbon-hydrogen bonds in heterocycles and electron-deficient arenes. Either selective monohalogenation or one-step exhaustive polyhalogenation is possible for substrates possessing several C-H bonds that are flanked by electron-withdrawing groups. For the most acidic arenes, such as pentafluorobenzene, K3PO4 base can be employed instead of BuLi for metalation/halogenation sequences.

In situ generation and trapping of aryllithium and arylpotassium species by halogen, sulfur, and carbon electrophiles

(Chemical Equation Presented) A general method has been developed for in situ trapping of arylmetal intermediates by halogen, sulfur, ketone, and aldehyde electrophiles affording the functionalization of the most acidic position in arene. Pentafluorobenzene, benzothiazole, and benzoxazole can be functionalized by using K3PO4 base. For less acidic arenes, tBuOLi base is required. Arenes with DMSO pKa values of 35 or less are reactive. 2009 American Chemical Society.

SPECTROMETRIE DE MASSE DE TRIAZOLIDES ET DE LEURS PRODUITS DE TRANSFORMATION PAR PYROLYSE-ECLAIR SOUS VIDE

Besides the formation of acylium ions, the molecular ions of 1-acyl-1,2,4-triazoles substituted (R) at position 3 lose competitively ketene and carbon monoxide after electron impact ionization, but the ketene loss dominates largely if R is a strong electr