1290538-90-7Relevant academic research and scientific papers
Novel chiral bridged azepanes: Stereoselective ring expansion of 2-azanorbornan-3-yl methanols
Wojaczyńska, Elzbieta,Turowska-Tyrk, Ilona,Skarzewski, Jacek
, p. 7848 - 7854 (2012)
The reaction of 2-azanorbornan-3-yl methanols under Mitsunobu or mesylation conditions with various nucleophiles led to a series of chiral-bridged azepanes with configuration at C-4 dependent on the configuration of the starting alcohol. High yielding, st
2-CYANOPYRROLIDINECARBOXAMIDE COMPOUND
-
Page/Page column 47-48, (2008/06/13)
A compound of the formula (I) or a pharmaceutically acceptable salt thereof: [wherein X1 and X2 each is independently lower alkylene; X3 is =CH2, =CHF or =CF2; R1 is substituent, R2 and R3 each is independently H or lower alkyl; n is 0, 1, 2, 3 or 4.] having the activity inhibiting DPP-IV activity. They are therefore useful in the treatment of conditions mediated by DPP-IV, such as NIDDM.
