1290542-75-4Relevant articles and documents
Palladium-catalyzed oxidative coupling of trialkylamines with aryl iodides leading to alkyl aryl ketones
Liu, Yan,Yao, Bo,Deng, Chen-Liang,Tang, Ri-Yuan,Zhang, Xing-Guo,Li, Jin-Heng
supporting information; experimental part, p. 2184 - 2187 (2011/06/20)
Chemical equations presented. A new, simple method for selectively synthesizing alkyl aryl ketones has been developed by palladium-catalyzed oxidative coupling of trialkylamines with aryl iodides. In the presence of PdCl2(MeCN)2, TBAB, and ZnO, a variety of aryl iodides underwent an oxidative coupling reaction with tertiary amines and water to afford the corresponding alkyl aryl ketones in moderate to excellent yields. It is noteworthy that this method is the first example of using trialkylamines as the carbonyl sources for constructing alkyl aryl ketone skeletons.