129055-68-1Relevant academic research and scientific papers
Diastereoselective trans Cyclopropanation of 3-Alkylidene Oxindoles with in Situ Generated α-Diazo Carbonyls or α,β-Unsaturated Diazo Compounds
Pramanik, Sayan,Ray, Suman,Maity, Suvendu,Ghosh, Prasanta,Mukhopadhyay, Chhanda
supporting information, p. 2240 - 2252 (2021/03/18)
An efficient diastereoselective trans cyclopropanation of 3-alkylidene oxindoles with in situ generated α-diazo carbonyl compounds or α,β-unsaturated diazo compounds under metal-free conditions has been developed to synthesize 3-spirocyclopropyl-2-oxindol
Autoxidation/Aldol Tandem Reaction of 2-Oxindoles with Ketones: A Green Approach for the Synthesis of 3-Hydroxy-2-Oxindoles
Zhang, Qing-Bao,Jia, Wen-Liang,Ban, Yong-Liang,Zheng, Yong,Liu, Qiang,Wu, Li-Zhu
, p. 2595 - 2598 (2016/02/27)
In the presence of tetrabutylammonium fluoride and molecular sieves (MS) 4 ? in DMF, an efficient autoxidation reaction of 2-oxindoles with ketones under air at room temperature has been developed. This approach may provide a green, practical, and metal-free protocol for a wide range of biologically important 3-hydroxy-3-(2-oxo-alkyl)-2-oxindoles.
A new and convenient synthetic way to 2-substituted thieno[2,3-b]indoles
Irgashev, Roman A.,Karmatsky, Arseny A.,Rusinov, Gennady L.,Charushin, Valery N.
, p. 1000 - 1007 (2015/08/19)
A short and robust approach for the synthesis of 2-(hetero)aryl substituted thieno[2,3-b]indoles from easily available 1-alkylisatins and acetylated (hetero)arenes has been advanced. The two-step procedure includes the "aldol-crotonic" type of condensatio
Synthesis and structure of new oxoindoles
Macaev,Radul,Shterbet,Pogrebnoi,Sucman,Malinovskii,Barba,Gdaniec
, p. 298 - 305 (2008/09/20)
The synthesis and study of the structure of new oxoindoles has been carried out. The molecular and crystal structure, and the stereochemistry atom of C(3) of 1,2-diacetyl-5′-phenyl(2′,4′ dihydrospiro[3H-indol-3, 3′-[3H]pyrazol]-2-(1H)-one have been establ
SOME REACTIONS OF N-ETHYLISATIN WITH METHYL KETONES
Metwally, Saoud A.,Younes, Mansour I.,Abbas, Hessin H.
, p. 591 - 598 (2007/10/02)
N-Ethylisatin (1) reacts with some methyl ketones such as acetophenone, 2-acethylthiophene and 2-acethylpyridine to give the corresponding addition products 2.Also, 1 reacts with active methylene derivatives such as oxindole, or 3-methyl-2-pyrazolin-5-one
