1290616-94-2Relevant academic research and scientific papers
Antidiabetic activity of dihydropyrimidine scaffolds and structural insight by single crystal x-ray studies
Alwassil, Osama I.,Bairagi, Keshab M.,Emeka, Promise Madu,Gonnade, Rajesh G.,Khalil, Hany Ezzat,Nayak, Susanta K.,Sangtani, Ekta,Venugopala, Katharigatta N.,Younis, Nancy Safwat
, p. 996 - 1003 (2020/08/19)
Background: This research project is designed to identify the anti-diabetic effects of the newly synthesized compounds to conclude the perspective of consuming one or more of these new synthetic compounds for diabetes management. Introduction: A series of
Synthesis and biological evaluation of novel homocamptothecins conjugating with dihydropyrimidine derivatives as potent topoisomerase i inhibitors
Zhu, Lingjian,Cheng, Pengfei,Lei, Ning,Yao, Jianzhong,Sheng, Chunquan,Zhuang, Chunlin,Guo, Wei,Liu, Wenfeng,Zhang, Yongqiang,Dong, Guoqiang,Wang, Shengzhang,Miao, Zhenyuan,Zhang, Wannian
scheme or table, p. 726 - 734 (2012/06/30)
Homocamptothecin (hCPT) is a camptothecin (CPT) homologue with the insertion of a methylene (-CH2-) spacer between the alcohol moiety and carbonyl group of the classical six-membered α-hydroxylactone ring. This modification provides higher lact
