1290636-73-5Relevant academic research and scientific papers
Discovery of meta-amido bromophenols as new antitubercular agents
Liang, Jie,Tang, Yun-xiang,Tang, Xiang-zheng,Liang, Hua-ju,Gao, Yamin,Fang, Cuiting,Zhang, Tian-yu,Yan, Ming
, p. 372 - 381 (2019/05/07)
A series of meta-amido bromophenol derivatives were designed and synthesized. The compounds were found to potently inhibit the growth of Mycobacterium tuberculosis H37Ra. They also exhibited moderate inhibitory activity against Mycobacterium tuberculosis H37Rv and multidrug-resistant strains. The compounds did not show inhibitory activity against normal Gram-positive and Gram-negative bacteria. Moderate cytotoxicities and good metabolic stability were observed for the selected compounds. The results demonstrated meta-amido bromophenols as a new class of antitubercular agents with good potentials.
N-(2-hydroxyaryl)benzamide synthesis from 2-nitroaryl benzoates via an Indium-mediated reduction-migration reaction
Lee, Hyejeong,Kim, Minki,Jun, Young Moo,Kim, Byeong Hyo,Lee, Byung Min
experimental part, p. 158 - 167 (2011/10/08)
A one-pot reduction-triggered N-(2-hydroxyaryl)benzamide synthesis from 2-nitroaryl benzoate substrates was investigated. In the presence of indium/AcOH in THF/H2O, 2-nitroaryl benzoates produced reasonable yields of the benzo group migrated N-
