129086-49-3Relevant academic research and scientific papers
Enantioselective Synthesis of a Chiral Intermediate for Aztreonam and Related Monobactam Antibiotics
Steen, Fred H. van der,Kleijn, Henk,Spek, Anthony L.,Koten, Gerard van
, p. 503 - 504 (1990)
The enantioselective synthesis of trans-(3R,4S)-1-(R)-α-methylbenzyl-3-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentyl)-4-N-(R)-α-methylbenzyliminoazetidin-2-one has been accomplished by reaction of the chlorozinc enolate of an N,N-diprotected glycine ethyl ester with a chiral α-diimine.
Enantioselective Synthesis of 3-Amino-2-azetidinones via the Ester Enolate-Imine Condensation
Steen, Fred H. van der,Kleijn, Henk,Britovsek, George J. P.,Jastrzebski, Johann T. B. H.,Koten, Gerard van
, p. 3906 - 3916 (2007/10/02)
Three approaches to the enantioselective synthesis of 3-amino-4-substituted-2-azetidinones by condensation of α-amino ester enolates with imines are described: (i) application of chiral ester derivatives of N,N-diethylglycine; (ii) application of chiral N
