129095-40-5

Basic information

• Product Name: 3-(4-(allyloxy)phenyl)-3-oxopropanenitrile
• Synonyms: 3-(4-(allyloxy)phenyl)-3-oxopropanenitrile
• CAS NO: 129095-40-5
• Molecular Weight: 201.225
• Mol File: 129095-40-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(4-(allyloxy)phenyl)-3-oxopropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-(allyloxy)phenyl)-3-oxopropanenitrile(129095-40-5)
• EPA Substance Registry System: 3-(4-(allyloxy)phenyl)-3-oxopropanenitrile(129095-40-5)

Safety Data

• Hazardous Substances Data: 129095-40-5(Hazardous Substances Data)

Usage

Type

Nitrile derivative of allyloxyphenyl ketone

Physical Form

White to off-white crystalline powder

Melting Point

96-98°C

Solubility

Soluble in organic solvents such as ethanol, methanol, and acetone

Applications

Intermediate in pharmaceutical and agrochemical industries
Building block in the synthesis of other organic compounds
Research tool in organic chemistry
Reagent in the production of pharmaceutical ingredients

Upstream product

• 120-47-8 Ethyl 4-hydroxybenzoate 
• 5443-37-8 ethyl 4-(n-prop-2'-enyloxy)benzoate 
• 75-05-8 acetonitrile 

Downstream Products

• 129095-27-8 6-cyclohexyl-6,7-dihydro-4-(phenylmethyl)-2-(4-(2-propenyloxy)phenyl)-4H-pyrazolo<1,5-a>pyrrolo<3,4-d>pyrimidine-5,8-dione 
• 130681-00-4 6-cyclohexyl-6,7-dihydro-4-(phenylmethyl)-2-(4-hydroxyphenyl)-4H-pyrazolo<1,5-a>pyrrolo<3,4-d>pyrimidine-5,8-dione 
• 129117-16-4 6-cyclohexyl-6,7-dihydro-2-(4-(2-propenyloxy)phenyl)-4H-pyrazolo<1,5-a>pyrrolo<3,4-d>pyrimidine-5,8-dione 
• 951790-64-0 5-(4-(allyloxy)phenyl)-1-(2,4-chlorophenyl)-4-cyano-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide 
• 951790-65-1 5-(4-(allyloxy)phenyl)-1-(2-bromophenyl)-4-cyano-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide 
• 921590-81-0 1-(2,4-dichlorophenyl)-4-cyano-5-(4-hydroxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide 
• 951790-66-2 1-(2-bromophenyl)-4-cyano-5-(4-hydroxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide 
• 951790-61-7 5-(4-(allyloxy)phenyl)-1-(2,4-dichlorophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid 
• 951790-62-8 5-(4-(allyloxy)phenyl)-1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid 
• 951790-58-2 ethyl 5-(4-(allyloxy)phenyl)-1-(2,4-dichlorophenyl)-4-cyano-1H-pyrazole-3-carboxylate 
• 951790-59-3 ethyl 5-(4-(allyloxy)phenyl)-1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylate 
• 129095-41-6 5-(4-(2-propenyloxy)phenyl)-1H-pyrazol-3-amine 

Relevant articles and documents

Synthesis of 1-(2,4-dichlorophenyl)-4-cyano-5-(4-[11C] methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide ([ 11C]JHU75528) and 1-(2-bromophenyl)-4-cyano-5-(4-[ 11C]methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-c

Two novel ligands for cerebral cannabinoid receptor (CB1), 1-(2,4-dichlorophenyl)-4-cyano-5-(4-methoxyphenyl)-N-(piperidin-1-yl) -1H-pyrazole-3-carboxamide (JHU75528) and 1-(2-bromophenyl)-4-cyano-5-(4- methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carb

Synthesis and Hypocholesterolemic Activity of 6,7-Dihydro-4H-pyrazolopyrrolopyrimidine-5,8-diones, Novel Inhibitors of AcylCoA:Cholesterol O-Acyltransferase

A novel series of 6,7-dihydro-4H-pyrazolopyrrolopyrimidine-5,8-dione inhibitors of the enzyme acylCoA:cholesterol O-acyltransferase is described.A number of these derivatives were found to be potent modulators of serum lipoprotein levels in