129101-37-7 Usage
Uses
Used in Pharmaceutical Industry:
(R)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications, particularly in the treatment of various diseases and conditions.
Used in Chemical Research:
In the field of chemical research, (R)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid serves as a key building block for the synthesis of complex organic molecules. Its reactivity and structural features make it an attractive candidate for the development of novel chemical entities with potential applications in various industries, including materials science, agrochemistry, and environmental science.
Used in Organic Synthesis:
(R)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid is used as a versatile reagent in organic synthesis, enabling the preparation of a wide range of chemical products. Its unique structure allows for various functional group transformations and reactions, making it a valuable tool for the synthesis of complex organic molecules with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 129101-37-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,1,0 and 1 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 129101-37:
(8*1)+(7*2)+(6*9)+(5*1)+(4*0)+(3*1)+(2*3)+(1*7)=97
97 % 10 = 7
So 129101-37-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H9FO3/c11-7-2-4-8-6(5-7)1-3-9(14-8)10(12)13/h2,4-5,9H,1,3H2,(H,12,13)/t9-/m1/s1
129101-37-7Relevant academic research and scientific papers
Preparation method of chromanone 2-carboxylic acid or chroman 2-carboxylic acid derivatives
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, (2017/05/16)
The present invention relates to a chromanone-2-carboxylic acid derivative and a chroman-2-carboxylic acid derivative which can be used as an intermediate for effective medicinal components currently available in the market, and to preparation methods the
An efficient and practical enantiospecific synthesis of methyl chromanone- and chroman-2-carboxylates
Kim, Dong Woon,Maqusood Alam,Lee, Young Hun,Khan, M. Naseer A.,Zhang, Yong,Lee, Yong Sup
, p. 912 - 917 (2015/08/24)
Chromanone-2-carboxylates and chroman-2-carboxylates are useful building blocks for the synthesis of a variety of bioactive compounds, such as repinotan, fidarestat, and nebivolol. An efficient and practical enantiospecific synthesis of chromanone-2-carboxylates and chroman-2-carboxylates has been accomplished using intramolecular Mitsunobu etherification of methyl (S)-2-hydroxy-4-oxo-4-(2′-hydroxy)phenylbutanoates derived from l-malic acid.
PROCESS FOR THE PREPARATION OF NEBIVOLOL
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Page/Page column 16-18, (2012/07/28)
The present invention relates to a novel process for the synthesis of the Nebivolol product depicted in Scheme 1, comprised of a reduced number of high-yield steps, and characterized by the enzymatic resolution of the chroman ester precursor.
Method of lowering the blood pressure
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, (2008/06/13)
A method of potentiating the effects of blood pressure reducing agents in warm-blooded animals, said method comprising administering to said warm-blooded animals of an effective amount of a blood pressure reducing agent and a 2,2′-iminobisethanol derivative.
