1291083-12-9Relevant academic research and scientific papers
Monosaccharide as a central scaffold toward the construction of salicylate-based bidentate PTP1B inhibitors via click chemistry
Tang, Yan-Hui,Hu, Min,He, Xiao-Peng,Fahnbulleh, Sando,Li, Cui,Gao, Li-Xin,Sheng, Li,Tang, Yun,Li, Jia,Chen, Guo-Rong
, p. 1000 - 1006 (2012/01/13)
The discovery of carbohydrate-based bioactive compounds has recently received considerable interest in the drug development. This paper stresses on the application of 1-methoxy-O-glucoside as the central scaffold, whereas salicylic pharmacophores were int
Microwave-assisted construction of triazole-linked amino acid-glucoside conjugates as novel PTP1B inhibitors
He, Xiao-Peng,Li, Cui,Jin, Xiao-Ping,Song, Zhuo,Zhang, Hai-Lin,Zhu, Cheng-Jiang,Shen, Qiang,Zhang, Wei,Sheng, Li,Shi, Xiao-Xin,Tang, Yun,Li, Jia,Chen, Guo-Rong,Xie, Juan
, p. 622 - 631 (2011/06/20)
There has been increasing interest in the development of protein tyrosine phosphatase 1B (PTP1B) inhibitors for the treatment of type 2 diabetes, obesity and breast cancer. We report here the identification of a series of mono- and bis-phenylalaninyl and
