129157-04-6

Upstream product

• 129157-01-3 tert-Butylamino-phenyl-acetic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 70111-05-6 (S)-2-chloro-1-phenylethanol 
• 75-64-9 tert-butylamine 
• 129157-03-5 L-menthyl (R)-2-t-butylamino-2-phenylethanoate 
• 41804-43-7 methyl 2-(tert-butylamino)-2-phenylacetate 

Downstream Products

• 129157-05-7 (R)-2-t-butylamino-1-methoxy-2-phenylethane 

Relevant academic research and scientific papers

Enantioselective nitrile anion cyclization to substituted pyrrolidines. A highly efficient synthesis of (3S,4R)-N-tert-butyl-4-arylpyrrolidine-3- carboxylic acid

(Chemical Equation Presented) A practical asymmetric synthesis of N-tert-butyl disubstituted pyrrolidines via a nitrile anion cyclization strategy is described. The five-step chromatography-free synthesis of (3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrr

ENANTIOSELECTIVE SYNTHESIS OF β-HYDROXY-α-METHYL CARBONYL COMPOUNDS BY ALDOL REACTION

The enantioselective aldol reactions of ketone lithium enolates with aldehydes mediated chiral lithium amides were extensively investigated.The chiral amino ethers 4a-4l and diamines 16a,b were prepared from α-amino acids.The reaction conditions and the s