129159-24-6Relevant articles and documents
Diethylaminosulphur Trifluoride (DAST) as an Effective Reagent for Preparation of Methyl 2-Arylpropanoates from 1-Aryl-1,1-dimethoxypropan-2-ols
Yamauchi, Takayoshi,Hattori, Kaneaki,Ikeda, Shun-ichi,Tamaki, Kentaro
, p. 1683 - 1685 (2007/10/02)
Treatment of dimethylacetals of aryl 1-hydroxyethyl ketones (Ar= Ph, 4-PhC6H4, 4-BuiC6H4, 4-MeOC6H4, 4-BrC6H4, 6-MeOnaphthalen-2-yl) with diethylaminosulphur trifluoride (DAST) affords smoothly the methyl 2-arylpropanoates in good yield via aryl-group migration.On the other hand, treatment of aryl 1-hydroxyethyl ketones with DAST gives the corresponding aryl 1-fluoroethyl ketones (Ar= Ph, 4-PhC6H4, 4-BuiC6H4) in high yield.