129170-27-0

Upstream product

• 129001-05-4 C₁₇H₂₇NO₄S₂ 

Downstream Products

• 125826-58-6 (1R,6R)-9-Aza-bicyclo[4.2.1]non-2-ene-2,9-dicarboxylic acid 9-tert-butyl ester 2-methyl ester 
• 125736-14-3 (1R)-9-(tert-butoxycarbonyl)-2-carboxy-9-azabicyclo<4.2.1>non-2-ene 
• 129099-04-3 C₁₄H₂₃NO₄ 
• 90741-49-4 (R)-2-Acetyl-9-aza-bicyclo[4.2.1]nonane-9-carboxylic acid tert-butyl ester 
• 129001-06-5 (R)-2-Chlorocarbonyl-9-aza-bicyclo[4.2.1]nonane-9-carboxylic acid tert-butyl ester 
• 125736-03-0 (R)-9-Aza-bicyclo[4.2.1]nonane-2,9-dicarboxylic acid 9-tert-butyl ester 
• 125736-10-9 9-Aza-bicyclo[4.2.1]non-2-ene-2,9-dicarboxylic acid 9-tert-butyl ester 2-methyl ester 
• 125736-37-0 2-Bromo-9-aza-bicyclo[4.2.1]nonane-2,9-dicarboxylic acid 9-tert-butyl ester 2-methyl ester 
• 125736-08-5 2-Phenylselanyl-9-aza-bicyclo[4.2.1]nonane-2,9-dicarboxylic acid 9-tert-butyl ester 2-methyl ester 

Relevant academic research and scientific papers

Enantiodivergent Synthesis of (+)- and (-)-Anatoxin from L-Glutamic acid

The optically pure 2,5-difunctionalized homotropane 11, prepared from L-glutamic acid, serves as the common, advanced intermediate for the synthesis of either natural (+)-anatoxin (30, 18percent overall yield) or unnatural (-)-anatoxin (33, 30percent overall yield) by selective manipulation of either the C-2 ester or C-5 acetyl functionalities.Side-chain substitution in the decarbonylative iminium ion cyclization of a substituted proline enhanced the yield by 25percent as compared to the unsubstituted parent system.The additional substitution at C-5 of the 9-azabicyclononane ring system allows access to analogues of anatoxin not availalble through other syntheses.