125736-14-3

Basic information

• Product Name: (1R)-9-(tert-butoxycarbonyl)-9-azabicyclo[4.2.1]non-2-ene-2-carboxylic acid
• CAS NO: 125736-14-3
• Molecular Formula: C₁₄H₂₁NO₄
• Molecular Weight: 267.3208
• Mol File: 125736-14-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 404.2°C at 760 mmHg
• Flash Point: 198.3°C
• Density: 1.201g/cm³
• Vapor Pressure: 1.15E-07mmHg at 25°C
• Refractive Index: 1.532
• CAS DataBase Reference: (1R)-9-(tert-butoxycarbonyl)-9-azabicyclo[4.2.1]non-2-ene-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1R)-9-(tert-butoxycarbonyl)-9-azabicyclo[4.2.1]non-2-ene-2-carboxylic acid(125736-14-3)
• EPA Substance Registry System: (1R)-9-(tert-butoxycarbonyl)-9-azabicyclo[4.2.1]non-2-ene-2-carboxylic acid(125736-14-3)

Safety Data

• Hazardous Substances Data: 125736-14-3(Hazardous Substances Data)

Usage

General Description

(1R)-9-(tert-butoxycarbonyl)-9-azabicyclo[4.2.1]non-2-ene-2-carboxylic acid is a chemical compound with the molecular formula C14H21NO4. It is a derivative of the naturally occurring compound 9-azabicyclo[4.2.1]nonane-2-carboxylic acid, which has potential pharmacological properties. This specific derivative contains a carbonyl group protected by a tert-butoxycarbonyl (Boc) group, which is commonly used in organic synthesis to protect amine functionalities. The compound's structural features suggest that it could potentially be used in the development of pharmaceuticals or as a building block for the synthesis of other biologically active compounds.

Upstream product

• 5259-72-3 cyclo-octa-1,5-diene 
• 1179812-42-0 C₂₃H₃₀N₂O₄S 
• 1179812-48-6 C₂₁H₂₉NO₄Se 
• 129170-27-0 C₁₅H₂₅NO₄ 
• 1179812-45-3 C₁₅H₂₅NO₄ 
• 1179812-38-4 C₁₄H₂₃NO₄ 
• 1379405-80-7 C₁₀H₁₇NO₂ 
• 125826-58-6 (1R,6R)-9-Aza-bicyclo[4.2.1]non-2-ene-2,9-dicarboxylic acid 9-tert-butyl ester 2-methyl ester 
• 125736-12-1 (1R)-9-(tert-butoxycarbonyl)-2-<2-(tert-butyldimethylsiloxy)-acetyl>-9-azabicyclo<4.2.1>non-2-ene 
• 125736-11-0 (1R)-9-(tert-butoxycarbonyl)-2-<1-(tert-butyldimethylsiloxy)-ethenyl>-9-azabicyclo<4.2.1>non-2-ene 
• 90741-53-0 (1R)-2-acetyl-9-(1-tert-butoxycarbonyl)-9-azobicyclo<4.2.1>-2-nonene 
• 125736-13-2 (1R)-9-(tert-butoxycarbonyl)-2-(2-hydroxyacetyl)-9-azabicyclo<4.2.1>non-2-ene 
• 67-56-1 methanol 

Downstream Products

• 125736-19-8 (1R,6R)-2-(Methoxyimino-methyl)-9-aza-bicyclo[4.2.1]non-2-ene-9-carboxylic acid tert-butyl ester 
• 125826-60-0 (1R,6R)-2-(Methoxyimino-methyl)-9-aza-bicyclo[4.2.1]non-2-ene-9-carboxylic acid tert-butyl ester 
• 125736-21-2 (1R)-anatoxinal 
• 125736-18-7 (1R,6R)-2-(Isoxazolidine-2-carbonyl)-9-aza-bicyclo[4.2.1]non-2-ene-9-carboxylic acid tert-butyl ester 
• 125736-16-5 (1R,6R)-2-Dimethylcarbamoyl-9-aza-bicyclo[4.2.1]non-2-ene-9-carboxylic acid tert-butyl ester 
• 125736-17-6 (1R,6R)-2-Methoxycarbamoyl-9-aza-bicyclo[4.2.1]non-2-ene-9-carboxylic acid tert-butyl ester 
• 125826-59-7 (1R)-9-(tert-butoxycarbonyl)-2-formyl-9-azabicyclo<4.2.1>non-2-ene 
• 125736-15-4 (1R)-9-(tert-butoxycarbonyl)-2-(chlorocarbonyl)-9-azabicyclo<4.2.1>non-2-ene 

Relevant articles and documents

Synthesis of a (+)-anatoxin-a analogue for monoclonal antibodies production

Anatoxin-a analogue was prepared by resolution of aminoacid 1 using chiral (R)-4-phenyl-oxazolidin-2-thione as derivatizing agent. X-ray diffraction of a diastereomer allowed us to determine its absolute configuration. The synthesis could then be complete