129222-25-9Relevant academic research and scientific papers
Sulfonamide-Trapping Reactions of Thermally Generated Benzynes
Wang, Yuanxian,Zheng, Lianyou,Hoye, Thomas R.
, p. 7145 - 7148 (2018)
Reactions of tethered, tertiary sulfonamides with thermally generated benzynes are reported. Typically, the N-S bonds in the substrates cleave, and saturated heterocycles [tetrahydroquinolines (n = 2) and indolines (n = 1)] are formed. The process is accompanied by either sulfonyl transfer or desulfonylation from a zwitterionic intermediate, with the favored pathway being largely dependent upon the size (5- vs 6-membered) of the N-containing ring in the zwitterion.
