1292282-98-4Relevant academic research and scientific papers
KDR inhibitor with the intramolecular non-bonded interaction: Conformation-activity relationships of novel indole-3-carboxamide derivatives
Honda, Takahiro,Nagahara, Hironori,Mogi, Hiroyuki,Ban, Masakazu,Aono, Hiroyuki
supporting information; experimental part, p. 1782 - 1785 (2011/05/05)
We previously reported that compound 1, having a similar conformation to PTK787 (2) by forming a pseudo ring structure with an intramolecular non-bonded S-O interaction, exhibited a potent inhibitory activity against VEGFR2 tyrosine kinase (KDR).1/s
