1292358-69-0Relevant academic research and scientific papers
Cu2O acting as a robust catalyst in CuAAC reactions: Water is the required medium
Wang, Kai,Bi, Xihe,Xing, Shuangxi,Liao, Peiqiu,Fang, Zhongxue,Meng, Xianyu,Zhang, Qian,Liu, Qun,Ji, Yu
, p. 562 - 565 (2011)
Cu2O as the catalyst in water was found to be quite robust for the azide-alkyne cycloaddition (AAC) reaction, which was verified by a wide variety of applicable azides and alkynes. Water was proved to play an essential role because of a significant rate acceleration compared with reactions using organic solvents and conducted under neat conditions. The high catalytic performance of Cu2O/H2O system was further argued by decreasing the catalyst loading to ppm levels. The Royal Society of Chemistry.
