1292358-72-5Relevant academic research and scientific papers
Polycyclic Indoline-Benzodiazepines through Electrophilic Additions of α-Imino Carbenes to Tr?ger Bases
Bosmani, Alessandro,Guarnieri-Ibá?ez, Alejandro,Goudedranche, Sébastien,Besnard, Céline,Lacour, Jér?me
, p. 7151 - 7155 (2018)
Polycyclic indoline-benzodiazepines can be accessed through the intermolecular reaction of Tr?ger bases with N-sulfonyl-1,2,3-triazoles. Under RhII catalysis, α-imino carbenes are generated and a subsequent cascade of [1,2]-Stevens, Friedel–Cra
Facile synthesis of N2-substituted-1,2,3-triazole from aryl ethynylene and azide via a one-pot two-step strategy
Guan, Cong,Ji, Jian,Li, Zi,Wei, Qinghua,Wu, Xiang,Liu, Shunying
, (2022/02/10)
An efficient one-pot two-step synthetic strategy to access highly selective N2-substituted-1,2,3-triazole from aryl ethynylenes, azides and furan has been developed via a radical transformation. 17 examples of aryl ethynylene with various substituents were converted into their corresponding functionalized N2-substituted-1,2,3-triazole derivatives in good yields.
Cu2O acting as a robust catalyst in CuAAC reactions: Water is the required medium
Wang, Kai,Bi, Xihe,Xing, Shuangxi,Liao, Peiqiu,Fang, Zhongxue,Meng, Xianyu,Zhang, Qian,Liu, Qun,Ji, Yu
supporting information; experimental part, p. 562 - 565 (2011/05/03)
Cu2O as the catalyst in water was found to be quite robust for the azide-alkyne cycloaddition (AAC) reaction, which was verified by a wide variety of applicable azides and alkynes. Water was proved to play an essential role because of a significant rate acceleration compared with reactions using organic solvents and conducted under neat conditions. The high catalytic performance of Cu2O/H2O system was further argued by decreasing the catalyst loading to ppm levels. The Royal Society of Chemistry.
