129238-73-9

Usage

Molecular weight

153.2 g/mol

Type of compound

Fluorinated derivative of tetrahydrobenzimidazole

Type of structure

Bicyclic heterocyclic compound

Availability

Not readily available, mainly used for research purposes

Potential applications

Medicinal chemistry, as a building block for the synthesis of compounds with potential pharmacological properties

Structural features

Fluorinated moiety, suitable for investigations in drug discovery and development

Further research needed

To fully understand the potential applications and properties of the compound.

InChI:InChI=1/C9H6F4N2/c10-7(9(11,12)13)8-14-5-3-1-2-4-6(5)15-8/h1-4,7H,(H,14,15)

Upstream product

• 116-15-4 perfluoropropylene 
• 95-54-5 1,2-diamino-benzene 

Relevant academic research and scientific papers

Synthesis of fluorine-containing benzimidazole derivatives

Various fluorine-containing benzimidazoles were obtained by the reaction of o-phenylenediamine, 3,4-diaminotoluene, and 1,2-diamino-4-chlorobenzene with hexafluoropropene or perfluoro(methyl vinyl ether) in DMF. A new efficient method of synthesis of 2-(1,2,2,2-tetrafluoroethyl)benzimidazole by the reaction of o-phenylenediamine with hexafluoropropene in the presence of diethylamine or dimethylamine in ethyl acetate is developed.

Monomers and polymers carrying imidazole and benzimidazole groupings, and proton exchange membrane containing the same for the production of a fuel cell

The invention relates to a monomer (6, 14) carrying an imidazole-type heterocycle (3). According to the invention, the chemical structure of said monomer (6, 14) comprises at least one unit of formula (I) wherein R1 comprises an alkenyl grouping and R2 comprises a grouping for protecting one of the nitrogen atoms of the heterocycle. The invention also relates to a monomer carrying a benzimidazole-type heterocycle, and to protected polymers obtained from said monomers, deprotected polymers produced by the protected polymers, a proton exchange membrane based on deprotected polymers, and a fuel cell provided with said membrane. Furthermore, the invention relates to methods for producing the above-mentioned monomers and polymers.