129242-47-3Relevant academic research and scientific papers
Synthesis of pyrido[1,2-a]benzimidazoles by photo-stimulated C-N bond formation via SRN1 reactions
Barolo, Silvia M.,Wang, You,Rossi, Roberto A.,Cuny, Gregory D.
, p. 5487 - 5494 (2013/06/27)
The photo-stimulated cyclization of 2-(2-halophenylamino)pyridines in liquid ammonia afforded pyrido[1,2-a]benzimidazoles via SRN1 mediated C-N bond forming reactions in moderate to excellent yields (58-94%). This general synthetic strategy was also extended to a 2-(2-bromophenylamino)pyrazine to give pyrazino[1,2-a]benzimidazole. Attempts to employ this reaction using N-(2-chlorophenyl)-3-isoquinolinamine, however, resulted in C-C bond formation generating 7H-indolo[2,3-c]isoquinoline.
Intramolecular Diels-Alder reactions of pyrazines with alkynylphenyl moieties as side-chain dienophiles
Haider, Norbert,Van Der Plas, Henk C.
, p. 3641 - 3650 (2007/10/02)
Intramolecular Diels-Alder reactions of (2-alkynylphenyl-X)-pyrazines (X = O, NAc, S) under neutral and acidic conditions are described. The isomer distribution of the resulting tricyclic b- and c-annelated pyridines is discussed.
