129242-97-3

Upstream product

• 532-20-7 L-arabinose 
• 98-88-4 benzoyl chloride 
• 55726-00-6 5-O-triphenylmethyl-L-arabinofuranose 
• 532-20-7 L(+)-arabinose 
• 131285-04-6 1,2,3-tri-O-benzoyl-5-O-trityl-L-arabinose 

Downstream Products

• 129242-98-4 O-(2,3,4-tri-O-acetyl-6-O-octyl-β-D-galactopyranosyl)-(1->5)-1,2,3-tri-O-benzoyl-L-arabinose 
• 131285-21-7 (S)-2-Benzyloxycarbonylamino-6-[(2S,3R,4S)-2,3,4-trihydroxy-5-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-octyloxymethyl-tetrahydro-pyran-2-yloxy)-pentylamino]-hexanoic acid 

Relevant academic research and scientific papers

Accelerated esterification of aminoacids with lipoglycosylated α-chymotrypsin in polar solvents

A lipodisaccharide possessing a reactive aldopentose function, the 6-O-octyl-β-D-galactopyranosyl-(1→5)-L-arabinose (5), has been prepared. The reductive alkylation of four of the lysine residues of the bovine α-chymotrypsin led to a lipo-1-deoxyglycytolated enzyme. This modified protein efficiently catalyzed the synthesis of N-acetyl aminoacid ethyl esters in different solvents with 2.5-3% water contents. Compared to the native enzyme, enhanced esterification rates were determined, particularly in tetrahydrofuran, ethyl acetate and acetonitrile.