129277-03-8 Usage
Uses
Used in Organic Chemistry:
(3E)-4-[(1S,4S,6R)-1,4-dihydroxy-2,2,6-trimethylcyclohexyl]but-3-en-2-one is utilized as a key intermediate in organic synthesis for the creation of complex organic molecules. Its unique bicyclic structure allows for versatile chemical reactions, making it a valuable component in the synthesis of novel compounds with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, (3E)-4-[(1S,4S,6R)-1,4-dihydroxy-2,2,6-trimethylcyclohexyl]but-3-en-2-one serves as a precursor for the development of new drugs. Its complex structure and potential biological activity suggest that it could be a promising candidate for the treatment of various diseases, pending further research into its pharmacological properties.
Used in Natural Product Synthesis:
(3E)-4-[(1S,4S,6R)-1,4-dihydroxy-2,2,6-trimethylcyclohexyl]but-3-en-2-one is employed as a building block in the synthesis of natural products. Its ability to mimic the structural features of naturally occurring compounds makes it an attractive option for researchers aiming to recreate or modify biologically active substances found in nature.
Further research and analysis are necessary to fully explore the properties and potential uses of (3E)-4-[(1S,4S,6R)-1,4-dihydroxy-2,2,6-trimethylcyclohexyl]but-3-en-2-one, as its complex structure and possible biological activities suggest a wide range of applications across different fields.
Check Digit Verification of cas no
The CAS Registry Mumber 129277-03-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,2,7 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 129277-03:
(8*1)+(7*2)+(6*9)+(5*2)+(4*7)+(3*7)+(2*0)+(1*3)=138
138 % 10 = 8
So 129277-03-8 is a valid CAS Registry Number.
129277-03-8Relevant academic research and scientific papers
Total synthesis and biological activities of (+)- and (-)-boscialin and their 1'-epimers
Busch, Joachim,Grether, Yvonne,Ochs, Dietmar,Sequin, Urs
, p. 591 - 597 (2007/10/03)
Natural (-)-boscialin [(-)-1] has recently been described as one of the constituents of various medicinal plants. To obtain more material for investigations of its biological activities, we carried out the synthesis of (-)-1 and its isomers. Starting from the chiral building block 2, the key steps of the synthesis involved a regioselective reduction and a nucleophilic addition. The enantiomer of the natural product, (+)-boscialin [(+)-1], could be obtained via acid-catalyzed epimerization of hydroxyketone 4 to (+)-3. Starting the synthesis with (-)-3 led to (-)-boscialin [(-)-1] with the natural absolute configuration. In addition to (+)- and (-)-boscialin, the corresponding 1'-epimers (+)- and (-)-epiboscialin were also obtained. In vitro assays with (-)-boscialin [(-)-1] and its three stereoisomers were carried out to test for activity against microbes, parasites, and human fibroblasts. The investigations revealed activity against various microbes and against Trypanosoma brucei rhodesiense and also revealed cytotoxicity against human cancer cells.
