1292780-69-8Relevant academic research and scientific papers
Diastereoselective trans Cyclopropanation of 3-Alkylidene Oxindoles with in Situ Generated α-Diazo Carbonyls or α,β-Unsaturated Diazo Compounds
Pramanik, Sayan,Ray, Suman,Maity, Suvendu,Ghosh, Prasanta,Mukhopadhyay, Chhanda
, p. 2240 - 2252 (2021/03/18)
An efficient diastereoselective trans cyclopropanation of 3-alkylidene oxindoles with in situ generated α-diazo carbonyl compounds or α,β-unsaturated diazo compounds under metal-free conditions has been developed to synthesize 3-spirocyclopropyl-2-oxindol
Eco-friendly Polyethylene Glycol-400 as a Rapid and Efficient Recyclable Reaction Medium for the Synthesis of Anticancer Isatin-linked Chalcones and Their 3-Hydroxy Precursor
Gupta, Alpana K.,Bharadwaj, Mausumi,Mehrotra, Ravi
, p. 703 - 709 (2018/12/11)
Isatin chalcones and their 3-hydroxy precursors are shown to possess potential anticancer activity and are also versatile substrates and key intermediates for the synthesis of a large variety of bioactive spiro-oxindoles. An environmental friendly tandem
Access to 3-Prenylated Oxindoles by α-Regioselective Prenylation: Application to the Synthesis of (±)-Debromoflustramine e
Li, De-Feng,Liu, Kun,Jiang, Yi-Xuan,Gu, Yan,Zhang, Jing-Ru,Zhao, Li-Ming
supporting information, p. 1122 - 1125 (2018/02/23)
The development of a rapid, highly efficient, and one-pot synthesis of C3-α-prenylated oxindoles with simple reagents is described. The process is based on zinc-mediated α-regioselective prenylation of 3-acylidene-oxindole with commercially available pren
Synthesis of novel spiropyrazoline oxindoles and evaluation of cytotoxicity in cancer cell lines
Monteiro, ?ngelo,Gon?alves, Lídia M.,Santos, Maria M.M.
, p. 266 - 272 (2014/05/06)
A series of novel spiropyrazoline oxindole derivatives was synthesized by 1,3-dipolar cycloaddition reaction. The compounds were screened for their in vitro cytotoxic activity against MCF-7 breast cancer cell line (estrogen receptor positive (ER+) and hum
Oxindole derivatives as inhibitors of TAK1 kinase
Lockman, Jeffrey W.,Reeder, Matthew D.,Robinson, Rosann,Ormonde, Patricia A.,Cimbora, Daniel M.,Williams, Brandi L.,Willardsen, J. Adam
scheme or table, p. 1724 - 1727 (2011/05/04)
Several series of oxindole analogues were synthesized and screened for inhibitory activity against transforming growth factor-β-activating kinase 1 (TAK1). Modifications around several regions of the lead molecules were made, with a distal hydroxyl group
Synthesis, spectroscopic characterization, and in vitro antimicrobial potency of sulfur-bonded complexes of boron(III)
Swami, Monika,Mahajan, Karuna,Gupta, Neeti,Singh,Arya, Sunita,Kushwah, Sonalika
experimental part, p. 2125 - 2139 (2010/02/28)
The present article describes the synthesis and characterization of tetracoordinated boron (III) complexes with monobasic bidentate ligands (L 1H, L2H, L3H, L4H, L5H, and L6H) having the ge
