1292783-85-7Relevant academic research and scientific papers
Selective Methylation of Arenes: A Radical C?H Functionalization/Cross-Coupling Sequence
Serpier, Fabien,Pan, Fei,Ham, Won Seok,Jacq, Jér?me,Genicot, Christophe,Ritter, Tobias
supporting information, p. 10697 - 10701 (2018/07/31)
A selective, nonchelation-assisted methylation of arenes has been developed. The overall transformation, which combines a C?H functionalization reaction with a nickel-catalyzed cross-coupling, offers rapid access to methylated arenes with high para selectivity. The reaction is amenable to late-stage methylation of small-molecule pharmaceuticals.
One-pot synthesis of pyrimidines via cyclocondensation of β-bromovinyl aldehydes with amidine hydrochlorides
Yan, Shengjiao,Tang, Yajuan,Yu, Fuchao,Lin, Jun
experimental part, p. 487 - 490 (2011/04/22)
A series of pyrimidines were prepared by cyclocondensation of β-bromovinyl aldehydes with amidine hydrochlorides in the presence of Et3N in excellent yields (74-95%).
