6326-27-8

Basic information

• Product Name: 4-Methylbenzene-1-carboximidamide hydrochloride
• Synonyms: BUTTPARK 43\57-87;4-METHYLBENZIMIDAMIDE, HCL;4-METHYLBENZENE-1-CARBOXIMIDAMIDE HYDROCHLORIDE;4-METHYLBENZAMIDINE HYDROCHLORIDE;4-methylbenzenecarboximidamidemonohydrochloride;4-toluamidinehydrochloride;p-toluamidine,monohydrochloride;4-Methylbenzene-1-carboximidamideHCl
• CAS NO: 6326-27-8
• Molecular Formula: C₈H₁₀N₂*ClH
• Molecular Weight: 170.64
• Product Categories: blocks;BuildingBlocks;Carboxes;Miscellaneous
• Mol File: 6326-27-8.mol
• Article Data: 10

Chemical Properties

• Melting Point: 211-214°C
• Boiling Point: 225°C at 760 mmHg
• Flash Point: 89.9°C
• Appearance: /
• Vapor Pressure: 0.0884mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: soluble in Methanol
• Sensitive: Hygroscopic
• CAS DataBase Reference: 4-Methylbenzene-1-carboximidamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methylbenzene-1-carboximidamide hydrochloride(6326-27-8)
• EPA Substance Registry System: 4-Methylbenzene-1-carboximidamide hydrochloride(6326-27-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39
• RTECS: XS4865000
• Hazardous Substances Data: 6326-27-8(Hazardous Substances Data)

Usage

Uses

4-Methylbenzimidamide, HCl

InChI:InChI=1/C8H10N2/c1-6-2-4-7(5-3-6)8(9)10/h2-5H,1H3,(H3,9,10)/p+1

Upstream product

• 39739-50-9 p-toluimidic acid methyl ester hydrochloride 
• 43002-64-8 ethyl 4-methylbenzimidate hydrochloride 
• 19227-13-5 p-toluamidoxime 
• 72525-60-1 hexamethyldisilazan 
• 104-85-8 para-methylbenzonitrile 

Downstream Products

• 14727-23-2 6-methyl-2-(4-methylphenyl)pyrimidin-4-one 
• 77232-20-3 6-phenyl-2-p-tolyl-3H-pyrimidin-4-one 
• 97513-48-9 4,6-dimethyl-2-(p-tolyl)pyrimidine 
• 84660-46-8 6-oxo-2-p-tolyl-1,6-dihydro-pyrimidine-4-carboxylic acid 
• 79382-86-8 2-(4-methylphenyl)-4-methyl-pyrimidine 
• 79957-45-2 4-o-Chlorobenzylidene-2-p-tolyl-2-imidazolin-5-one 
• 125772-57-8 4-methylbenzamidinium trifluoracetate 
• 21139-61-7 2-(4-methylphenyl)-4,6-dichloropyrimidine 
• 77232-38-3 4-(2-pyrimidinyl)-benzaldehyde 
• 77232-37-2 2-(4-Bromomethyl-phenyl)-pyrimidine 
• 77232-14-5 4,6-Dimethoxy-2-(p-tolyl)pyrimidin 
• 77232-22-5 2-(4-methylphenyl)-4-phenylpyrimidine 
• 77232-17-8 2-(p-Brommethyl-phenyl)-4,6-dimethoxypyrimidin 
• 77232-18-9 4,6-Diethoxy-2-p-tolyl-pyrimidine 

Relevant articles and documents

Silver-catalyzed [3+2+1] annulation of aryl amidines with benzyl isocyanide

A silver-catalyzed [3+2+1] annulation of amidines with benzyl isocyanide toward 2,4-diaryl-1,3,5-triazines was developed. A variety of symmetrical and unsymmetrical products were obtained in moderate to good yields. This work also features an oxidant-free approach to 2,4-disubstituted triazines.

Synthesis and structure of aroylamidines and N-arylbenzamidines hydrochlorides

Aroylamidines can be obtained as salts in a reaction of the corresponding arylcarbonitriles with anhydrous ethanol in the presence of dry HCl followed by treating intermediate imidoesters with alcoholic solution of ammonia. N-Arylbenzamidines are obtained by reacting benzonitrile with arylamines in the presence of AlCl3. The structure of arylamines and the reaction conditions signifi cantly affect the yield of the target product, and sometimes the very possibility of its preparation. Pleiades Publishing, Ltd., 2012.

Dimerization and trapping of diazirinyl radicals

Computational and experimental methods have been utilized to examine the facile dimerization of diazirinyl radicals. Two potential dimers were investigated using density functional theory. Both were shown to have low-barrier reaction coordinates leading t