1292846-41-3Relevant academic research and scientific papers
One-pot synthesis and antimicrobial activity of novel naphthyridine derivatives
Zheng, Hui,Liu, Juan,Zhang, Pengfei
, p. 658 - 660 (2011/03/20)
A one-pot synthetic route was developed to synthesise novel naphthyridine derivatives from amino acids and a series of new naphthyridines was prepared and characterised by IR, 1H NMR, MS and elemental analysis. The preliminary bioassay results reveal that they have medium antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, Aspergillus, Escherichia coli and Monilia albican. The compounds containing aliphatic amino acids have greater bioactivity than that of those containing aromatic amino acids against Bacillus subtilis and Staphylococcus aureus.
