1292849-61-6

Basic information

• Product Name: 6,7-dihydro-5-phenyl-5H-dibenz[c,e]azepine
• Synonyms: 6,7-dihydro-5-phenyl-5H-dibenz[c,e]azepine
• CAS NO: 1292849-61-6
• Molecular Weight: 271.362
• Mol File: 1292849-61-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6,7-dihydro-5-phenyl-5H-dibenz[c,e]azepine(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dihydro-5-phenyl-5H-dibenz[c,e]azepine(1292849-61-6)
• EPA Substance Registry System: 6,7-dihydro-5-phenyl-5H-dibenz[c,e]azepine(1292849-61-6)

Safety Data

• Hazardous Substances Data: 1292849-61-6(Hazardous Substances Data)

Upstream product

• 1292816-64-8 t-butyl N-(diphenylmethyl)-N-[(2-bromophenyl)methyl]carbamate 
• 1292849-59-2 t-butyl 5-phenyl-5H-dibenz[c,e]azepine-6(7H)-carboxylate 
• 21420-61-1 N-(tert-butoxycarbonyl)(diphenylmethyl)amine 
• 91-00-9 Benzhydrylamine 

Relevant articles and documents

Atroposelective formation of dibenz[c,e]azepines via intramolecular direct arylation with centre-axis chirality transfer

5-Substituted 6,7-dihydrodibenz[c,e]azepines, a class of secondary amine incorporating a centre-axis chirality relay, are accessible from 1-substituted N-(2-bromobenzyl)-1-phenylmethanamines via N-acylation and ring-closing intramolecular direct arylation. The ring closure proceeds with high atropodiastereoselectivity due to strain effects that are induced by trigonalisation of the nitrogen atom, as predicted using molecular mechanics calculations.