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N-α-Fmoc-N-δ-trityl-L-glutamine N-carboxyanhydride is a specialized chemical compound utilized in the field of peptide synthesis. It is a derivative of the amino acid glutamine, which is an integral component of proteins. N-α-Fmoc-N-δ-trityl-L-glutamine N-carboxyanhydride features a fluorenylmethyloxycarbonyl (Fmoc) protecting group at the α-amino group and a trityl protecting group at the δ-amino group of the glutamine molecule. As an N-carboxyanhydride, it possesses reactivity that enables ring-opening reactions with nucleophilic groups, facilitating the creation of peptide bonds in solid-phase peptide synthesis processes.

129288-38-6

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129288-38-6 Usage

Uses

Used in Pharmaceutical Research and Development:
N-α-Fmoc-N-δ-trityl-L-glutamine N-carboxyanhydride is employed as a key intermediate in the synthesis of peptides for research purposes. It is particularly valuable for the development of novel pharmaceutical compounds, given its ability to form stable peptide bonds that are crucial for the structure and function of potential drug candidates.
Used in Peptide Synthesis for Drug Production:
In the pharmaceutical industry, N-α-Fmoc-N-δ-trityl-L-glutamine N-carboxyanhydride is used as a building block for the assembly of complex peptide sequences. Its role in solid-phase peptide synthesis is to provide a protected glutamine unit that can be selectively deprotected and incorporated into growing peptide chains, contributing to the production of therapeutic peptides and proteins.
Used in Academic Research:
N-α-Fmoc-N-δ-trityl-L-glutamine N-carboxyanhydride is also utilized in academic research settings to explore the fundamentals of peptide chemistry and to develop new methodologies for peptide synthesis. Its unique properties make it a valuable tool for studying the mechanisms of peptide bond formation and the effects of protecting groups on synthesis efficiency and yield.

Check Digit Verification of cas no

The CAS Registry Mumber 129288-38-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,2,8 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 129288-38:
(8*1)+(7*2)+(6*9)+(5*2)+(4*8)+(3*8)+(2*3)+(1*8)=156
156 % 10 = 6
So 129288-38-6 is a valid CAS Registry Number.

129288-38-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-α-Fmoc-N-δ-trityl-L-glutamine N-carboxyanhydride

1.2 Other means of identification

Product number -
Other names Fmoc-Gln(Trt)-NCA

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129288-38-6 SDS

129288-38-6Downstream Products

129288-38-6Relevant academic research and scientific papers

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